In addition to genetic leads to of those syndromes, In addition there are instances exactly where the Snrpn/Ube3A cluster is intact but its genes are epigenetically misregulated. This really is for instance the case if both homologs of chromosome 15 originate through the same mother or father, a situation named uniparental disomy (UPD). Maternal UP
Aside from genetic brings about of these syndromes, You will also find scenarios where the Snrpn/Ube3A cluster is intact but its genes are epigenetically misregulated. That is for instance the case if both of those homologs of chromosome fifteen originate within the similar mum or dad, a ailment known as uniparental disomy (UPD). Maternal UPD is ch
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